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Arnold Lab Research Group

Our research group works at the interface of computational and experimental biology to generate systems-level insight into the immune system, for potential use in development of new therapeutics and diagnostics.  Of special interest are mucosal surfaces in the female reproductive tract and the lung where the immune system is the first line of defense against infection but also contributes to problematic inflammatory processes.  Specific areas of interest include:

  1. Understanding complex immune processes involved in infectious disease susceptibility at mucosal surfaces in the female reproductive tract.
  2. Elucidating systems-level mechanisms of inflammation at pulmonary mucosal surfaces that contribute to asthma, COPD and pulmonary fibrosis.  
  3. Identification and design of immune microenvironments that best support tissue-engineered constructs and organ transplant.